Photo: Mulberry Street in Little Italy in 1900s. Little Italy, a neighborhood in lower Manhattan, New York City, was once known for its large population of Italians. Now much of it has been engulfed by Chinatown as a large number of immigrants from China moved to Little Italy. Currently the section of Mulberry Street, between Broome and Canal Streets, is all that is left of the old Italian neighborhood. The street is lined with about two dozen Italian restaurants, which are popular with tourists. In 2010, Little Italy and Chinatown were listed together as a single historic district on the National Register of Historic Places, the United States government's official list of districts, sites, buildings, structures and objects deemed worthy of preservation.